Currently no early method of detecting dengue in patients
Currently, only accurate early diagnosis of knowing if you have dengue is using blood samples to be analyzed at the labs. The usual scenario is waiting for days not knowing if the patient has dengue. Day 2 slight temperature, patients will see a doctor and most cases paracetamol will be prescribed. Day 3-4 significant increased temperature, patients will see a doctor again and most probably blood samples sent to labs. Day 5-6 blood palette count dropped significantly, by then patients are in a critical stage and to be rushed to the hospital. Hence the challenge is to detect the presence of dengue in patients as early as Day 4 rather than wait 3-4 later.
Currently, severe dengue diagnosis relies on careful clinical assessment for timely and appropriate management to prevent fatalities. Continuous patient monitoring often leads to prolonged hospitalisation which increases the cost of hospitalisation and insufficient hospital beds during outbreaks. The annual economic burden due to dengue in Malaysia is ~USD128 million and a high disease burden at 8324 disability-adjusted life-years (DALYs). Globally, 3.6 billion people at risk for dengue. In Malaysia, 80,615 dengue cases and 147 fatalities were reported in 2018 and with a continuous rise this year, the severe dengue test kit marketability is high. Unnecessary hospitalisation, fatalities and socioeconomic burden from loss of productivity and high hospitalisation costs.