A Quorum Sensing Inhibitor Biosensor, Method And Use Thereof

1. Technology Overview

The present invention relates to a quorum biosensor. More particularly, 5 the present invention relates to a biosensor for use in detecting short chain N-acyl homoserine lactone synthase inhibitor, characterized in that, the biosensor is an N-acyl homoserine lactone-producing Escherichia coli comprising an arabinose-dependent expression plasmid, its method of manufacturing and method of use thereof. The present invention provides a novel approach for the development of short-chain N-acyl homoserine lactone synthase inhibitor biosensor that is capable of detecting specific compounds, in particular, non-antibiotic compounds, which can be used in controlling quorum sensing-mediated bacterial infection.

  • UMCIC File Number: 603/784
  • Patent: PI 2016 702117
  • Patent status: Pending
  • Malaysia patent: A Quorum Sensing Inhibitor Biosensor, Method And Use Thereof
  • This technology is currently available for licensing and commercialisation.